GA Number: 101016167

Title: Connecting European Cohorts to Increase Common and Effective Response to SARS-CoV-2 Pandemic.

Design: Population based, prospective and retrospective cohort study.

Background: ORCHESTRA provides an innovative approach to learn from the pandemic SARS-CoV-2 crisis and form recommendations to improve further management of COVID-19 and be prepared for the possible future pandemic waves.

The ORCHESTRA project aims to respond to this need through the creation of a new pan-European cohort built on existing and new large-scale population cohorts in European (France, Germany, Spain, Italy, Belgium, Romania, Netherlands, Luxemburg, and Slovakia) and non-European countries (India, Perú, Ecuador, Colombia, Venezuela, Argentina, Brazil, Congo and Gabon).

The knowledge gleaned from the study of these cohorts will inform European strategies with regards to:

effective protection of fragile populations in Europe (e.g children, pregnant women, the elderly, solid organ transplant recipients, Alzheimer patients, oncological patients, Parkinson disease patients, patients with mental illness, HIV positive subjects)
reduction of the risks for frontline health care staff
longer-term consequences of COVID-19 on the health and well-being of individuals;
vaccination response
impact of environmental factors, socio-economic determinants, lifestyle and confinement measures on the spread of COVID-19

Update: In August 2023 the project was given a 12 month, no-cost extension.

Francesco Luca