VALUE-DX

Start Date

April 2019

Duration

48 months

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Title: The value of diagnostics to combat antimicrobial resistance by optimising antibiotic use


Design:

  1. Systematic reviews of the existing evidence for community-acquired acute respiratory tract infections (CA-ARTI) diagnostic tests.

  2. Integration of data from stakeholders’ consultation using multi-criteria decision analyses.

  3. Machine-learning-driven clinical algorithm development.

Registration Number: PROSPERO Number: CRD42019145282


Primary Objective: to develop clinical algorithms for the diagnosis of CA-ARTI


Secondary Objective(s): n.a.


Interested in collaboration? Contact Fulvia Mazzaferri, fulvia.mazzaferri@aovr.veneto.it, Anna Gorska, anna.gorska@univr.it, Elisa Gentilotti, elisa.gentilotti@univr.it, Pasquale De Nardo, pasquale.denardo@univr.it, Eleonora Cremonini, eleonora.cremonini@univr.it


Publications:

1.      Nucleic acid amplification tests on respiratory samples for the  diagnosis of coronavirus infections: a systematic review and  meta-analysis.

Mona Mustafa Hellou , Anna Górska, Fulvia Mazzaferri , Eleonora Cremonini, Elisa Gentilotti, Pasquale De Nardo, Itamar Poran, Mariska M Leeflang, Evelina Tacconelli, Mical Paul   

PMID: 33188933


2.    Multi-Criteria Decision Analysis to prioritize hospital admission of patients affected by COVID-19 in low-resource settings with hospital-bed shortage.               

De Nardo P, Gentilotti E, Mazzaferri F, Cremonini E, Hansen P, Goossens H, Tacconelli E; members of the COVID-19MCDA Group.   

PMID: 32619766 

Partners

University of Antwerp (Coordinator),
Fondazione PENTA (PENTA),
The Health Corporation (RAMBAM),
Universidad De La Rioja (UNIRIOJA),
University Medical Center Groningen (UMCG),
University Medical Center Utrecht (UMCU),
University of Edinburgh (UK),
University of Oxford,
University of Verona

ID-CARE

  • Anna Gorska

  • Elisa Gentilotti

  • Evelina Tacconelli

  • Fulvia Mazzaferri

  • Pasquale De Nardo