Title: The value of diagnostics to combat antimicrobial resistance by optimising antibiotic use

Design:

1. Systematic reviews of the existing evidence for community-acquired acute respiratory tract infections (CA-ARTI) diagnostic tests.

2. Integration of data from stakeholders’ consultation using multi-criteria decision analyses.

3. Machine-learning-driven clinical algorithm development.

Registration Number: PROSPERO Number: CRD42019145282

Primary Objective: to develop clinical algorithms for the diagnosis of CA-ARTI

Secondary Objective(s): n.a.

Interested in collaboration? Contact Fulvia Mazzaferri, fulvia.mazzaferri@aovr.veneto.it, Anna Gorska, anna.gorska@univr.it, Elisa Gentilotti, elisa.gentilotti@univr.it, Pasquale De Nardo, pasquale.denardo@univr.it, Eleonora Cremonini, eleonora.cremonini@univr.it

Publications:

1.      Nucleic acid amplification tests on respiratory samples for the  diagnosis of coronavirus infections: a systematic review and  meta-analysis.

Mona Mustafa Hellou , Anna Górska, Fulvia Mazzaferri , Eleonora Cremonini, Elisa Gentilotti, Pasquale De Nardo, Itamar Poran, Mariska M Leeflang, Evelina Tacconelli, Mical Paul   

PMID: 33188933

2.    Multi-Criteria Decision Analysis to prioritize hospital admission of patients affected by COVID-19 in low-resource settings with hospital-bed shortage.               

De Nardo P, Gentilotti E, Mazzaferri F, Cremonini E, Hansen P, Goossens H, Tacconelli E; members of the COVID-19MCDA Group.   

PMID: 32619766