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High rate of pulmonary thromboembolism in patients with SARS-CoV-2 pneumonia

Minuz P, Mansueto G, Mazzaferri F, Fava C, Dalbeni A, Ambrosetti MC, Sibani M, Tacconelli E

To the Editor,

Recently, thromboembolic events have been reported in 20 of 81 individuals with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) severe pneumonia admitted to intensive care units. About 90% of patients showed an increased coagulation activity, including high D-dimer concentrations, which demonstrated 85% sensitivity and 89% specificity for identifying groups at high risk for thromboembolic events. Moreover, cytokine storm syndrome has been proposed to cause a hypercoagulable state in individuals with coronavirus disease 2019 (COVID-19)...

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